Rechallenge combo for metastatic colorectal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of three drugs (cetuximab, irinotecan, and envafolimab) as a ‘rechallenge’ – meaning if you had good results with cetuximab or irinotecan before, trying them again with a new drug might help shrink or control your cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have metastatic colorectal cancer (cancer that has spread).
- A recent blood test shows your cancer is RAS and BRAF wild-type (no specific gene mutations).
- You have had a good response (tumor shrank or disappeared) to previous treatment with cetuximab or irinotecan.
- It has been at least 2 months since your last dose of cetuximab.
- You are generally active (ECOG performance status 0 or 1) and your organs are working well enough.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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