Testing SPI-1005 with cochlear implant surgery
Part of Brain & nervous system, Ear, nose & throat clinical trials.
This trial tests an oral medication, SPI-1005, given to adults receiving a cochlear implant to see if it improves hearing outcomes. It may help people with moderate to profound hearing loss who are scheduled for implant surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have moderate to profound hearing loss in both ears that developed after you learned to speak, and be scheduled for a cochlear implant in one ear.
- Your hearing test must show certain levels: low tones (125-500 Hz) no worse than 70 decibels, and high tones (2000-8000 Hz) at least 70 decibels or worse.
- Your ear receiving the implant must have normal middle ear function (Type A tympanogram).
- You must not have used certain strong medications (like chemotherapy or specific antibiotics) within the past 60 days.
- You must not be pregnant, breastfeeding, or have significant liver problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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