Testing MANP for hard-to-control high blood pressure
Part of Heart & circulation clinical trials.
This trial tests a new drug called MANP for people whose blood pressure stays high despite taking three or more different types of blood pressure medications. The goal is to see if MANP is safe and effective in lowering blood pressure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 80 years old
- Be taking at least 3 blood pressure medications, including a water pill (diuretic) and an ACE inhibitor or ARB at moderate doses
- Have a seated blood pressure reading of 140 or higher (systolic) before starting the study
- Have kidney function (eGFR) of 30 or above, or between 20-30 in some cases
- Have a body mass index (BMI) between 18 and 40
- Not be able to become pregnant (if female) or agree to use birth control (if male) during and after the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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