Study of manp for hard-to-control high blood pressure
Part of Heart & circulation clinical trials.
This study tests a new investigational drug called MANP to see if it can lower blood pressure in people whose blood pressure stays high even when they are already taking several medications. If it works, this drug might offer a new option for people with difficult-to-control hypertension.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You are taking at least two different blood pressure medicines, including a water pill (diuretic) and an ACE inhibitor or ARB, and your blood pressure is still high (systolic at least 140).
- You have moderate kidney function (eGFR of 30 or higher; a small number of people with slightly lower kidney function may also be eligible).
- You are not pregnant, not planning to become pregnant, and if you could get someone pregnant, you agree to use a condom with spermicide during the study and for 90 days after.
- You have not had a heart attack, stroke, or heart rhythm problems in the last 6 months, and you do not have heart failure or a pacemaker.
- You are not on dialysis, have not had a kidney transplant, and do not have certain causes of secondary high blood pressure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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