Modified release RTN-001 for uncontrolled high blood pressure
Part of Heart & circulation clinical trials.
This trial tests a new modified-release drug, RTN-001, to see if it can help people whose blood pressure remains high despite taking at least two standard blood pressure medicines. You will take either RTN-001 or a placebo, and researchers will monitor your blood pressure closely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- Your blood pressure is still high (≥130/80) even though you take two or more blood pressure medicines (like ACE inhibitors, beta blockers, or water pills) and the doses have been steady for at least 30 days.
- You are not taking nitrates, alpha-blockers, or certain diabetes drugs (SGLT2 inhibitors or GLP-1 agonists), or you can stop them for the study.
- You have no recent heart attack, stroke, or uncontrolled heart rhythm problems (within the last 3 months).
- You are not using erectile dysfunction drugs (PDE5 inhibitors) regularly and are willing to stop them during the study.
- Your kidney function is normal (eGFR ≥45) and you have no active liver disease or history of drug or alcohol abuse.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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