Study of two drugs before surgery for upper tract cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests a combination of two drugs, enfortumab vedotin and pembrolizumab, given before surgery for upper tract urothelial cancer. The goal is to see if this treatment can shrink the tumor and improve outcomes for patients who are candidates for surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with high-grade upper tract urothelial cancer (in the kidney pelvis or ureter).
- You are healthy enough for surgery and have not had previous immune therapy or certain other cancer treatments.
- You are 18 years or older and able to perform daily activities with minimal help (ECOG 0-1).
- You have adequate organ function and no active infections or certain eye conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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