Low dose sedation medicine for pain after scoliosis surgery
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests a low dose of a sedative medicine, dexmedetomidine, given during and after spine surgery to see if it helps with pain. It is for teens and adults with scoliosis having back fusion surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have idiopathic scoliosis (curved spine with no known cause)
- You are scheduled for a posterior spinal fusion (back surgery) that joins at least 5 vertebrae in both the upper and lower back
- You are not allergic to dexmedetomidine or standard surgery medicines
- You are not currently taking opioid pain medicine, TCA antidepressants, or gabapentinoids (nerve pain drugs)
- You do not have unstable heart problems, a long QT interval on EKG, life-threatening arrhythmias, or take digoxin
- You do not have Moya Moya disease (a rare blood vessel disorder in the brain)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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