Lower radiation dose for children with CNS germinoma
Treatments studied
Part of Cancer, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial will see if giving a lower dose of radiation therapy can still effectively treat children and young adults with a type of brain tumor called germinoma. The goal is to reduce side effects while keeping the cancer under control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 3 and 30 years old.
- You must have a newly diagnosed, localized germinoma in certain areas of the brain (like the pineal or suprasellar region).
- Your blood or spinal fluid must have certain levels of tumor markers (HCG-beta and AFP) that are within specific ranges.
- You must be in generally good health (able to carry out daily activities) with adequate kidney, liver, and blood cell counts.
- You cannot have received any prior cancer treatment for this germinoma, except for surgery or steroids.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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