Clin2
NCT06372964Possibly a fitRecruiting

Lumateperone for pediatric bipolar depression

Bipolar Depression

Treatments studied

Part of Mental health clinical trials.

This study tests a new medication called lumateperone for treating depression in children and teens with bipolar disorder. It aims to see if this drug can help improve mood and daily functioning.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
384 people
Ages
10 years to 17 years
Study type
Interventional

Who can take part

  • Your child must be between 10 and 17 years old.
  • They must have a diagnosis of bipolar I or bipolar II disorder and be currently experiencing a depressive episode without psychosis.
  • The current depressive episode must have lasted at least 4 weeks but less than 12 months.
  • Your child should not have a primary diagnosis other than bipolar disorder (ADHD is okay if stable on meds for 30 days).
  • They must not be at high risk for suicide or have had a manic episode in the last 30 days.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06690398Recruiting· Phase 3
Study of Lumateperone for Autism-Related Irritability in Teens

This study tests a new medication called Lumateperone to see if it can reduce irritability in children and teens with autism. It's a 3-month trial that compares the study drug to a placebo (a pill with no active medicine) to find out if it helps with mood and behavior.

Dothan, Alabama
NCT07747389Not yet recruiting· Phase 3
Lumateperone for major depressive disorder

This study tests whether the drug lumateperone can help people with moderate to severe depression. If you join, you may receive the study drug or a placebo (a pill with no active medicine) to see if it improves your symptoms.

NCT06229210Recruiting· Phase 3
Lumateperone safety study for children with schizophrenia, bipolar, or autism

This trial tests a medication called lumateperone for children and teens with schizophrenia, bipolar disorder, or autism spectrum disorder. It aims to see if the medicine is safe and tolerable over time.

Phoenix, Arizona
NCT07623135Recruiting· Phase 3
Lumateperone for Hard-to-Treat Depression in Older Adults

This study tests lumateperone, a new medication added to your current antidepressant, to help treat depression that hasn't improved with other treatments. It's designed for people age 60 and older who have tried at least two antidepressants without success.

Tucson, Arizona
NCT07699445Not yet recruiting· Phase 4
Lumateperone for weight and mood in bipolar depression

This study tests if lumateperone, a medication for bipolar depression, can also help with weight and aging in people with obesity. You may qualify if you have bipolar I depression and a body mass index (BMI) over 30.

Boston, Massachusetts
NCT05850689Recruiting· Phase 3
Lumateperone add-on for major depression that didn’t improve

This study tests whether adding lumateperone to an antidepressant helps adults with major depressive disorder (MDD) who haven’t improved enough after trying at least two different antidepressants. It may help reduce depressive symptoms more than antidepressants alone.

Huntsville, Alabama

Hear when a new Bipolar Depression trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.