Two medicines vs one for brain parasite infection
Treatments studied
Part of Brain & nervous system, Infections clinical trials.
This trial tests whether a combination of two medicines (praziquantel and albendazole) works better than one medicine (albendazole alone) for treating a parasitic brain infection that causes seizures. Participants will be hospitalized for up to 20 days and followed for one year to see how well the infection clears and if symptoms improve.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and have lived in the study area for the past 3 years.
- You have a type of brain infection called active neurocysticercosis that is causing symptoms like seizures.
- The cysts in your brain are only in the main brain tissue, not in the fluid-filled spaces around the brain.
- You are not pregnant or breastfeeding.
- You are willing to stay in the hospital for 11 to 20 days to start treatment and be followed for one year afterward.
- You haven't had any allergic reaction before to the study drugs (albendazole or praziquantel).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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