Giving antibiotic through bone vs. vein during ankle replacement
Treatments studied
Part of Infections clinical trials.
This study tests whether giving the antibiotic vancomycin through a small needle in the bone instead of a vein is safe and works well during total ankle replacement surgery. It may help you if you are having this surgery and want to prevent infection in a new way.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are scheduled for a total ankle replacement surgery
- You can give your own permission to join the study
- You are not allergic to vancomycin, cefepime, or cefazolin (Ancef)
- Your diabetes is well-controlled (A1C below 7.5) or you do not have diabetes
- You do not have a weakened immune system (from HIV, hepatitis C, kidney failure, dialysis, transplant, or recent cancer treatment)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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