Intraosseous Vancomycin in Knee Replacement Surgery
Part of Bones, joints & muscles clinical trials.
This study tests a new way to deliver antibiotics directly into the bone during knee replacement surgery to prevent infection. Vancomycin is injected into the bone marrow instead of through an IV, which may help protect the surgical site better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older and receive care at UC San Diego
- You are having your first total knee replacement surgery on one knee only
- You can give your informed consent to participate
- Your doctor believes intraosseous (bone-injection) antibiotic delivery is appropriate for you
- You have not had previous surgery on the same knee (except minor arthroscopy)
- You do not have a severe allergy to vancomycin, cefepime, or cefazolin antibiotics
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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