Vancomycin in bone during knee replacement surgery
Part of Bones, joints & muscles clinical trials.
This study tests giving the antibiotic vancomycin directly into the bone during knee replacement surgery to see if it helps prevent infections. If you are scheduled for a first-time knee replacement, this could help lower your risk of infection after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older and receiving care at UC San Diego
- You are scheduled for your first total knee replacement on the affected knee (a prior simple knee scope may be okay)
- Your body mass index (BMI) must be 35 or less
- You cannot be allergic to vancomycin or related antibiotics
- You must not have poorly controlled diabetes (A1c above 7.5%)
- You must not have a weakened immune system or an active infection
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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