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NCT06387082Possibly a fitRecruiting

Study of an investigational pill for certain leukemias

Hematological Malignancies

Part of Blood & lymphatic, Cancer clinical trials.

This study tests an experimental pill (HMPL-506) for people with certain types of leukemia (AML or ALL) that have not responded to standard treatments. The pill targets specific gene changes (MLL rearrangement or NPM1 mutation) to try to kill the cancer cells.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
132 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older.
  • You must have a type of leukemia (AML or ALL) that has come back or not responded to treatment, with a specific gene change (MLL rearrangement or NPM1 mutation).
  • You must be in good enough health to be up and active (able to take care of yourself or up more than half the day).
  • You cannot have had a menin inhibitor drug before or have active cancer in the brain or spine.
  • You must agree to bone marrow tests and use birth control if there is any chance of pregnancy.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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