Chemotherapy after surgery for thymic cancer
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests whether additional chemotherapy after surgery can help prevent thymic cancer from coming back. It is for people who have had their thymus tumor completely removed and are in good health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You had surgery to remove thymic cancer within the last 3 months, and the entire tumor was removed.
- Your cancer is at stage I, II, or III (Masaoka staging).
- Your blood counts and organ function (liver, kidneys, heart, lungs) are in good shape.
- You do not have another active cancer, serious heart disease, or drug/alcohol addiction.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial combines surgery (burning away the tumor) with heated chemotherapy given directly into the chest to treat thymus gland tumors that have spread to the lining of the lung or chest wall. The goal is to remove the visible tumor and wash the area with heated chemo to help delay or prevent it from coming back.
This trial tests whether adding an immunotherapy drug called adebrelimab to chemotherapy and radiation before surgery can help shrink thymic cancer and improve outcomes. It is for people with locally advanced thymic carcinoma that can potentially be removed with surgery.
This trial tests a shorter course of radiation therapy (fewer, larger doses) given after surgery for thymic tumors. The goal is to reduce the chance of the tumor returning while keeping side effects manageable.
This trial looks at adding radiation after a complete surgery to remove a thymoma (a tumor from the thymus) at stages II or III. It may help lower the chance the cancer comes back by treating leftover microscopic disease after surgery.
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