Internal radiation for rectal preservation in intermediate rectal cancer
Part of Cancer, Digestive system clinical trials.
This study is testing whether a special internal radiation treatment (contact X-ray brachytherapy) can help people with intermediate-stage rectal cancer avoid surgery and keep their rectum intact. It is for patients who are also receiving mFolfirinox chemotherapy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of rectal adenocarcinoma (a type of rectal cancer).
- Your tumor was found to be at an intermediate stage—not too small or too large, and with certain features—at the time of diagnosis.
- The tumor is located in the lower or middle part of the rectum, reachable by a doctor's exam, and does not involve the anal sphincter.
- You are physically well enough to have surgery (if needed) and are able to start or have already started a chemotherapy regimen called mFolfirinox.
- Your overall health and blood test results meet certain safety standards, such as good liver and kidney function, and adequate blood cell counts.
- You are not pregnant or breastfeeding, and you agree to use effective contraception during the study and for a period after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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