Clin2
NCT06405646Possibly a fitEnrolling by invitation

Cannabidiol and Cannabinol for Chronic Jaw Muscle Pain

MyalgiaMuscle PainOrofacial PainHeadache, TensionHeadaches Muscular

Part of Bones, joints & muscles, Brain & nervous system, Pain clinical trials.

This study tests whether certain compounds from the cannabis plant (CBD and CBN) can help relieve long-term pain in the jaw muscles. It is for adults with chronic orofacial pain who have not recently taken medications that affect the nerves or muscles.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
102 people
Ages
18 years to 80 years
Study type
Observational

Who can take part

  • You are between 18 and 80 years old.
  • You have had chronic pain in your jaw muscles for more than 3 months.
  • You are not pregnant or breastfeeding.
  • You are not obese.
  • You do not have active cancer or severe systemic, genetic, or neurological diseases.
  • You have not taken antidepressants, muscle relaxants, or similar drugs in the last year, and you do not have a severe mental illness or substance abuse problem.
  • You have not had a major head or face injury.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05961501Enrolling by invitation· Phase 2/Phase 3
CBD and CBN for long-lasting facial pain and muscle headaches

This trial tests whether CBD and CBN can reduce facial pain and headaches caused by muscle-related problems that have lasted more than 3 months. It may help people who have ongoing symptoms find a new treatment option.

Wroclaw
NCT07511959Enrolling by invitation
Blood-derived treatment for chronic jaw pain

This trial tests whether a treatment made from your own blood (platelet-rich plasma exosomes) can help relieve long-term jaw joint pain and improve function. If you qualify, you would receive injections directly into your jaw area.

Wroclaw
NCT05676827Enrolling by invitation
Study pain and stress in people with long-term jaw muscle pain

This trial looks at how long-lasting jaw (masticatory) muscle pain relates to the nervous system and emotional stress. It may help researchers understand why symptoms persist and guide future treatments.

Wroclaw
NCT06617494Recruiting
Study of pain control in chronic jaw pain

This study looks at how well the body's natural pain control system works in people with long-term jaw pain (TMD). It compares people with and without jaw pain to better understand why some have trouble turning off pain signals.

Minneapolis, Minnesota
NCT07153107Not yet recruiting
Jaw muscle pain study for adults

This study tests a jaw muscle assessment (phenotype) to better understand chronic jaw muscle pain. It may help if you have had jaw pain for more than 3 months with frequent episodes.

Minneapolis, Minnesota
NCT06357702Recruiting
Physical Self-Regulation vs Placebo for Chronic Jaw Pain

This study tests whether a physical self-regulation treatment (like relaxation or biofeedback) can help reduce chronic jaw muscle pain. It compares the treatment to a placebo (inactive) version to see if it works better.

Lexington, Kentucky

Hear when a new Myalgia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.