Resorbable airway splint trial for severe tracheobronchomalacia in children
Part of Bones, joints & muscles, Genetic & congenital, Lungs & breathing, Skin clinical trials.
This trial tests a new bioresorbable airway splint for babies and young children with severe tracheobronchomalacia (a weak, collapsing windpipe). It aims to help them breathe without a machine or tracheostomy and avoid major surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Must have severe tracheobronchomalacia (collapsing airway) with less than 50% open space in the windpipe or main bronchi.
- Must be unable to come off a breathing machine, need a tracheostomy, or be a candidate for one.
- Must be between 1 week and 4 years old.
- Must have a life expectancy of at least 2 years (not counting this airway problem).
- Must have a parent or guardian who can consent and a doctor willing to provide follow-up for 2 years.
- Must not have certain other lung, heart, or structural problems listed in the trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a special CT scan can help diagnose tracheomalacia (a condition where the airway collapses during breathing) in children who have already had a bronchoscopy.
This trial tests a surgery called posterior tracheopexy to prevent the windpipe from collapsing in babies with esophageal atresia and tracheomalacia. It may help your child breathe more easily.
This trial tests a new way to repair a child's windpipe using a piece of donated aorta (a blood vessel) as a patch. It's for children who have severe breathing problems from a narrowed or damaged windpipe and cannot have standard surgery.
This trial is testing a special device that may improve breathing for very premature babies who need a breathing machine. It aims to help their lungs work better by clearing out extra air (dead space) from the breathing tube.
This trial studies care during placing a breathing tube (tracheal intubation) in children having general anesthesia. It may help improve safety and outcomes around the breathing tube process.
This trial tests a surgery to repair the windpipe (trachea) or its branches (carina) without using a breathing tube during the procedure. It may help patients with certain airway diseases who are healthy enough to avoid traditional breathing support during surgery.
Hear when a new Tracheobronchomalacia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.