Treating hormone therapy pain in early breast cancer
Treatments studied
Part of Bones, joints & muscles, Cancer, Pain, Skin clinical trials.
This trial tests whether two supportive medicines (duloxetine and furosemide) can help reduce muscle, bone, or joint pain caused by hormone therapy in people with early breast cancer. If you are having this side effect, the study aims to improve your daily comfort and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be a woman or man with early-stage, hormone-receptor-positive breast cancer that is HER2-negative.
- You must have been getting hormone therapy (like tamoxifen or an aromatase inhibitor) for at least 3 months and plan to continue.
- You must have moderate to severe muscle, bone, or joint pain (pain that makes daily tasks harder) that has lasted at least 4 weeks.
- You cannot have severe depression or anxiety, or be taking antidepressants or water pills that might interfere with the study drugs.
- You need to have good kidney and liver function, and not have other serious health issues that could get worse with the study treatments.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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