Lactoferrin for heart failure with low iron
Part of Heart & circulation, Hormones & metabolism clinical trials.
This study tests whether adding the natural protein lactoferrin to usual heart-failure treatment improves symptoms and heart function in people with heart failure and low iron levels. Lactoferrin helps the body use iron, which may reduce tiredness and shortness of breath.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have had heart failure for more than 6 months with a weakened heart pump (ejection fraction 40% or lower).
- You feel short of breath or tired with mild to moderate activity (NYHA class II–IV) but your symptoms have been stable for at least 3 months.
- You are already taking standard heart-failure medicines (like beta-blockers, ACE inhibitors, ARBs, ARNIs, MRAs, or SGLT2 inhibitors) with no dose changes in the last 2 weeks.
- Your blood tests show low iron levels (ferritin between 15 and 100 ng/mL, or 101–299 ng/mL with low transferrin saturation).
- You have not taken iron supplements in the last 3 months and do not have anemia requiring transfusion (hemoglobin below 7 g/dL).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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