Tranexamic acid to reduce drainage after spinal fusion
Treatments studied
Part of Injuries & trauma clinical trials.
This trial tests whether putting a medicine called tranexamic acid (which helps reduce bleeding) on the surgery site can lessen the fluid that drains after a common type of lower-back spinal fusion surgery. It's for people having a single-level minimally invasive fusion, and it might help you recover with less drainage and fewer complications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 30 and 80 years old.
- You have a spine problem like a narrow spinal canal, worn-out discs, or a slipped vertebra, and you need surgery on one level of your lower back.
- You are not taking blood-thinning or anti-clotting medicines for at least 7 days before the surgery.
- You do not have a bleeding disorder, severe kidney or liver disease, or a history of blood clots or seizures.
- You are not allergic to tranexamic acid (a medicine that helps stop bleeding).
- You have not had spine surgery in the same area before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether tranexamic acid (a medicine that helps blood clot) can reduce blood loss during long spine surgery after an injury. It may help lower the chance of needing transfusions and manage surgical bleeding.
This trial studies whether giving tranexamic acid (a medicine that helps reduce bleeding) during planned lower-back decompression surgery can lower blood loss or related complications. It compares patients who receive the infusion during surgery to those who meet study procedures and safety requirements.
This trial studies whether a single dose or multiple doses of tranexamic acid (TXA) can reduce the chance you need a blood transfusion after spine fusion surgery. It also compares two different ways TXA may be given (by mouth and through a vein) to see which approach works best and is safe.
This Phase 3 trial tests whether tranexamic acid can reduce bleeding during major spine fusion surgery for adults with scoliosis or spine degeneration. It may help lessen blood loss and the need for transfusions, while monitoring safety.
This study tests whether giving tranexamic acid (a drug that helps blood clot) intravenously or directly into the surgical wound reduces drainage after breast reduction surgery. It may help you heal faster and avoid complications.
This trial tests if a medicine called tranexamic acid can help reduce bleeding during surgery for lung cancer that has spread to the spine. It may be an option if you have a single tumor in your spine and are having separation surgery.
Hear when a new Surgical Wound trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.