Tranexamic acid for less bleeding during spine surgery
Treatments studied
Part of Injuries & trauma clinical trials.
This trial tests if a medicine applied directly to the spine during a common type of back surgery (MI-TLIF) can reduce the amount of fluid that needs to be drained afterward. Tranexamic acid (TXA) helps blood clot, so using it this way may help you heal with less drainage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 30 and 80 years old.
- You have a degenerative spine problem like spinal stenosis, a worn disc, or a slipped vertebra (spondylolisthesis) that your doctor plans to treat with a single-level MI-TLIF surgery.
- You have not had spine surgery at the same level before.
- You are not at high risk for bleeding or complications from tranexamic acid (TXA), including no history of seizures, blood clots (like DVT or PE), or allergy to TXA.
- You have no major kidney disease (GFR less than 45), liver disease, or a bleeding disorder.
- You are not taking blood thinners (anticoagulants or antiplatelet drugs) within 7 days before surgery, and your blood clotting tests and platelet count are normal.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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