Propranolol for Kaposi Sarcoma in adults
Treatments studied
Part of Cancer, Infections clinical trials.
This trial tests if the blood pressure medication propranolol can treat Kaposi Sarcoma (a type of skin cancer) in adults. You may be able to join if you have at least 7 measurable skin lesions and are otherwise healthy enough to take an oral pill.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Kaposi Sarcoma confirmed by biopsy, with at least 7 measurable skin bumps (lesions) on your body.
- You are 18 years or older and weigh at least 88 pounds (40 kg).
- You are generally able to care for yourself (ECOG score 0-2).
- If you have HIV, you must be on anti-HIV therapy for at least 12 weeks.
- You are not pregnant, breastfeeding, or planning to become pregnant, and you agree to use birth control during the study and for 1 month after.
- You can swallow pills and are willing to follow the study plan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether the beta-blocker medicine propranolol can control Kaposi sarcoma (KS). It may help shrink KS lesions and slow disease when standard cancer medicines aren’t urgently needed.
This trial tests paclitaxel plus pegylated liposomal doxorubicin (two IV chemotherapy medicines) for HIV-related Kaposi sarcoma (KS). It may help shrink KS lesions and improve quality of life in people with certain stages of KS and enough heart, blood, and liver function to safely receive treatment.
This Phase 1/2 study tests PDS01ADC, a targeted cancer drug, for advanced Kaposi sarcoma (KS). It also studies how well the drug works when added to the immunotherapy M7824, especially if KS has not responded to prior treatments.
This trial tests an experimental drug (CYT107) that boosts the immune system to help fight Kaposi sarcoma in people with HIV who have a low CD4 count despite good HIV treatment. It aims to see if the drug can improve KS tumors and quality of life.
This Phase 1/2 study tests the medicine abemaciclib to shrink Kaposi sarcoma (KS) lesions and control the disease. It includes both people with HIV and people without HIV, and may help when KS has not responded well to prior treatment or when certain KS stages are present.
This trial studies ixazomib (a targeted anti-cancer medicine) to treat cutaneous (skin) Kaposi sarcoma. It aims to shrink measurable skin lesions and improve symptoms, especially in people living with HIV.
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