Doxycycline for brain tuberculosis
Treatments studied
Part of Brain & nervous system, Infections clinical trials.
This trial tests whether adding the antibiotic doxycycline to standard treatment can improve recovery in patients with tuberculosis of the brain (TB meningitis). It may help reduce brain swelling and damage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 21 years old or older.
- You have started TB treatment within the last 7 days or are about to start.
- You have been diagnosed with TB meningitis (definite, probable, or possible).
- Your liver function (ALT) is less than 3 times the normal upper limit.
- You are not pregnant or breastfeeding and have no active cancer or autoimmune disease on immune-suppressing drugs.
- You are not allergic to tetracycline antibiotics (like doxycycline).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 3 trial tests whether adding doxycycline to standard TB medicine can improve lung function and reduce lung tissue damage. It aims to see if patients recover better by targeting the lung response to TB.
This trial tests if giving a stronger combination of TB drugs for meningitis can save more lives. It's for patients who have been diagnosed with tuberculosis meningitis and have not yet started more than 5 days of TB treatment.
This trial tests whether the antibiotic doxycycline can prevent lung scarring (fibrosis) after a serious TB infection. You may be eligible if you are currently being treated for active TB and have significant lung damage on your chest X-ray.
This trial tests a new antibiotic called contezolid for people with tuberculous meningitis, an infection of the brain lining. The goal is to see if it works well and is safe.
This trial tests an intensified, shorter treatment plan for TB meningitis (TB in the lining around the brain) in adults, including people with HIV. It may help some patients get better with a structured plan while researchers compare treatment outcomes and safety.
This trial tests a new combination of drugs (alpibectir plus ethionamide) for people with tuberculosis meningitis (TB meningitis), a serious infection of the brain and spinal cord lining. It aims to see if the combination works better than standard treatment.
Hear when a new Tuberculosis, Meningeal trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.