A new valve device for severe tricuspid regurgitation
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests a new device called TricValve, which is placed through a catheter (a thin tube) to fix a leaky tricuspid valve on the right side of the heart. It aims to reduce blood flowing backward and improve heart failure symptoms for people who can't have open-heart surgery and haven't been helped by other catheter treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years old or older (there's also a group for people over 85).
- You need to have severe tricuspid regurgitation (a leaky valve on the right side of your heart) that causes blood to flow backward.
- You should have heart failure symptoms (like shortness of breath or swelling) or have been in the hospital for heart failure in the past 6 months.
- You must be on stable heart failure medications, including water pills (diuretics).
- You need to be considered too high-risk for open-heart surgery but suitable for a catheter-based procedure, and you haven't been able to use other approved catheter treatments.
- You should be able to walk at least 100 meters (about the length of a football field) in 6 minutes, and you must not have certain severe health issues (like very low heart pumping function, severe kidney disease, or recent major heart events).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new device to help people with severe tricuspid regurgitation (leaky heart valve) who are at higher risk from surgery. It aims to see if the device can reduce the leak and improve symptoms.
This study tests a new device to fix a leaky tricuspid valve without open-heart surgery. It is for people with severe leakage who are considered too high-risk for traditional surgery.
This trial tests a new device that replaces a leaky tricuspid valve (a heart valve) without open-heart surgery. If your tricuspid valve isn't working well and medicines haven't helped enough, this procedure might improve your heart function and symptoms.
This trial tests a catheter-based procedure (done through the blood vessels) to repair a severely leaky tricuspid valve. It may help people with symptoms or past hospitalizations from tricuspid valve leakage who are higher-risk for standard surgery.
This trial tests how well a new catheter-based valve system works for people with severe (or worse) tricuspid valve leaking who still have symptoms despite medicines. It aims to improve outcomes by treating the leaking valve without open-heart surgery, if your heart structure and overall health fit the study.
This trial studies a new valve replacement device (the Cor TRICUSPID ECM Valve) for people whose right-sided tricuspid valve is leaking or missing and needs surgery. It may help restore proper one-way blood flow in the heart, but you must meet several heart, blood, and organ-health requirements.
Hear when a new Tricuspid Valve Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.