Clinical trials
Tricuspid Valve Disease clinical trials
Below are recruiting tricuspid valve disease clinical trials, each written for real people, not researchers. We’re tracking 66 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07761273Enrolling by invitation
Tricuspid valve repair using heart tissue
This study tests a new way to repair the tricuspid valve (the valve that controls blood flow on the right side of your heart) using a piece of your own heart tissue called the right atrial appendage. This might be an option for people who need this type of valve surgery.
Zagazig, Sharqia ProvinceAges 18–70 - NCT06591000Recruiting
Comparing two types of tricuspid valve replacements
This trial compares two types of replacement valves for the tricuspid valve: a donated human valve (allograft) and a stented biological valve (made from animal tissue). The goal is to see which works better and lasts longer.
ChelyabinskAges 18–70 - NCT07433504Recruiting
Tricuspid valve clipping for leaky valve
This trial tests a new device that clips the tricuspid valve to stop blood from flowing backward. It is for people with severe tricuspid regurgitation (a leaky valve) who still have symptoms despite medical treatment.
ShanghaiAges 18 years+ - NCT02397668Recruiting
New tricuspid valve replacement for leaky or absent valve
This study tests a special replacement valve (an “ECM valve”) for people whose tricuspid valve is leaky or missing and needs surgery. It may help restore blood flow on the right side of the heart and is designed for certain children born with congenital heart problems.
Mobile, AlabamaAges 1–85 - NCT06506942Recruiting
TRICURE device study for leaky heart valve
This study tests a new device to help people with severe tricuspid regurgitation (leaky heart valve) who are at higher risk from surgery. It aims to see if the device can reduce the leak and improve symptoms.
Atlanta, GeorgiaAges 18 years+ - NCT03546231Recruiting
Understanding Tricuspid Valve Leakage: A Research Study
This study looks at people with moderate or severe leakage in the tricuspid valve (a valve in the right side of the heart) to understand how the condition develops and what outcomes patients experience. Researchers want to learn more about this condition so they can improve care.
AmiensAges 1.5 years+ - NCT04097145Recruiting
Heart valve repair for severe leaking tricuspid valve
This trial tests a catheter-based procedure (done through the blood vessels) to repair a severely leaky tricuspid valve. It may help people with symptoms or past hospitalizations from tricuspid valve leakage who are higher-risk for standard surgery.
Phoenix, ArizonaAges 18 years+ - NCT04436653Recruiting
New valve procedure for severe right-sided leakage
This trial tests whether a new minimally invasive valve replacement device (put through a catheter) can improve health in people with severe right-sided tricuspid valve leaking. It’s for patients who are considered too high-risk for standard open-heart tricuspid surgery.
Beijing, Beijing MunicipalityAges 50 years+ - NCT05114850Recruiting
Follow-up study for people treated with TricValve
This study looks back at patients who were successfully treated with TricValve bicaval valve devices and then follows up with their outcomes. You might join if you (or your legal guardian) agree to be included.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT05194423Recruiting
LuX-Valve procedure for severe leaking tricuspid valve
This trial tests a minimally invasive procedure (LuX-Valve placed through a neck vein) to treat severe leaking of the tricuspid valve. It may help people who are too high-risk for open-heart tricuspid surgery.
Beijing, Beijing MunicipalityAges 50 years+ - NCT05742906Recruiting
Tricuspid valve repair using a new replacement valve patch
This trial studies a new valve replacement device (the Cor TRICUSPID ECM Valve) for people whose right-sided tricuspid valve is leaking or missing and needs surgery. It may help restore proper one-way blood flow in the heart, but you must meet several heart, blood, and organ-health requirements.
Indianapolis, IndianaAges Any age - NCT05797519Recruiting
Transcatheter valve replacement for leaking tricuspid valve
This trial studies a catheter-based procedure to replace the tricuspid valve in people with severe valve leakage. It aims to improve symptoms and heart function while tracking safety and effectiveness.
Sydney, New South WalesAges 18 years+ - NCT05848284Recruiting
Tricuspid valve replacement to reduce leaking in the heart
This trial tests a new catheter-based procedure that replaces the tricuspid valve to reduce severe valve leaking. It may help people who still have symptoms despite heart medicines, but only if their heart shape and other health details fit the device requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05913908Recruiting
Valve procedure study for severe tricuspid leakage
This trial tests how well a new catheter-based valve system works for people with severe (or worse) tricuspid valve leaking who still have symptoms despite medicines. It aims to improve outcomes by treating the leaking valve without open-heart surgery, if your heart structure and overall health fit the study.
Phoenix, ArizonaAges 18 years+ - NCT06001489Recruiting
Virtual reality for anxiety before heart surgery
This trial tests whether watching a 360-degree virtual reality video can help reduce anxiety before heart surgery. If you are waiting for elective heart surgery and are at least 18 years old, you may be able to participate.
Amsterdam, North HollandAges 18 years+ - NCT06025149Recruiting
Study of a New Biological Heart Valve 'UniLine'
This study tests a new biological heart valve called 'UniLine' for people who need to replace their mitral valve (the valve between the left heart chambers) or aortic valve (the main valve sending blood to the body) for the first time. If you qualify, you would have planned surgery (not an emergency) and need to be free of certain other serious health conditions.
Kemerovo, Kemerovo OblastAges 18–80 - NCT06033274Recruiting
Global registry for tricuspid valve replacement
This study is a registry that collects data on patients who receive a new type of heart valve replacement for the tricuspid valve through a less invasive catheter procedure. Joining helps doctors learn more about how well this treatment works in real-world patients.
Phoenix, ArizonaAges 18 years+ - NCT06137807Recruiting
TricValve for severe tricuspid regurgitation
This trial is testing a new device called the TricValve to treat severe tricuspid regurgitation (a leaky heart valve on the right side). It is for people who still have symptoms despite taking heart failure medications.
Phoenix, ArizonaAges 18 years+ - NCT06235385Recruiting
European study on multiple and mixed valve disease
This study looks at people with multiple or mixed heart valve disease (moderate or severe) using echocardiography. It aims to learn more about how these conditions affect patients and help guide future care.
Paris, Île-de-France RegionAges 18 years+ - NCT06387446Recruiting
Donated heart valve transplant for children and young adults
This study is testing a new way to replace a damaged heart valve using a donated valve (allograft) that may last longer and work better for children and young adults. It may be a good option if you need a new valve and have few other choices.
Boston, MassachusettsAges 4 weeks–50 years - NCT06569602Recruiting
EVOQUE valve study for leaky tricuspid valve
This study is testing a new way to replace the tricuspid valve (the valve that controls blood flow from the heart's right upper chamber to the right lower chamber) without open-heart surgery. The goal is to see how safe and effective the EVOQUE valve is for people with a leaky tricuspid valve.
Bad OeynhausenAges Any age - NCT06581471Recruiting
New device for severe leaky heart valve
This study tests a new device to fix a leaky tricuspid valve without open-heart surgery. It is for people with severe leakage who are considered too high-risk for traditional surgery.
AalstAges 18 years+ - NCT07691307Recruiting
TruGamma tricuspid valve replacement study
This trial tests a new device called TruGamma to replace the tricuspid valve without open-heart surgery. It is for older adults with severe tricuspid regurgitation who cannot have surgery and still have symptoms despite medication.
Beijing, Beijing MunicipalityAges 65 years+ - NCT07267117Recruiting
Heart valve disease progression and outcomes study
This study is following people with heart valve disease (leaky or narrowed valves) to understand how the disease changes over time and what problems it may cause. It does not test a new treatment, but helps doctors learn more about valve disease progression.
Fuzhou, FujianAges 18 years+
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Tricuspid Valve Disease trials by city
Studies with a site in or near these metro areas.
Tricuspid Valve Disease trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for tricuspid valve disease?
- Yes. Clin2 currently lists 66 recruiting tricuspid valve disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tricuspid valve disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tricuspid valve disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.