Closing the left atrial appendage to reduce stroke risk
Part of Heart & circulation clinical trials.
This trial tests a procedure to close off a small pouch in the heart called the left atrial appendage, which is a common source of blood clots in people with atrial fibrillation. The goal is to lower your stroke risk without needing to take blood thinners long-term.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have atrial fibrillation (a type of irregular heartbeat) that is not caused by a reversible condition
- You have a high risk for stroke or blood clots
- Long-term use of blood thinners is not a good option for you, though you can take them for a short time
- You have not had certain heart procedures or conditions that would prevent the left atrial appendage closure procedure
- You have not had a recent stroke, mini-stroke, heart attack, or major surgery (within the past month)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a device that closes off a small pouch in the heart where blood clots can form in people with atrial fibrillation. This may help reduce the risk of stroke without needing long-term blood thinners.
This study compares two ways of closing a small pouch in the heart (the left atrial appendage) to help prevent strokes in people with atrial fibrillation (an irregular heartbeat). One method is less invasive, and the study aims to see if it is as safe and effective as the standard approach.
This study tests whether closing a heart pouch called the left atrial appendage can prevent future strokes in people with atrial fibrillation who had an ischemic stroke even while taking blood thinners. It may help reduce stroke risk by blocking a common place where clotting can start.
This trial tests the Zenith system, a device that seals off a heart area called the left atrial appendage to reduce stroke risk in people with atrial fibrillation (AF). You may be eligible if you have AF and a doctor recommends LAA closure, and you can return for follow-up scans and visits.
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
This study tests a device and procedure to close off a small pouch in the heart (left atrial appendage) where blood clots can form in people with atrial fibrillation. The goal is to reduce the risk of stroke, possibly lowering the need for long-term blood thinners.
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