Testing a new device to close the left atrial appendage in AFib
Part of Heart & circulation clinical trials.
This trial tests a new device called ENDOMATIC SEPIOLA that closes a small pouch in your heart (the left atrial appendage) to lower your stroke risk. It is a non-surgical option for people with atrial fibrillation who cannot take blood thinners.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have atrial fibrillation (AFib) that is not caused by a heart valve problem.
- Your doctor has calculated your stroke risk score (CHA2DS2-VASc) to be 2 or higher.
- You cannot take blood thinners, or you have a reason to avoid them (like side effects or bleeding risk).
- Your heart's left atrial appendage (a small pouch in your heart) must have the right shape and size for the device – your doctor will check this.
- You do not have other severe heart conditions, such as a prosthetic valve, a hole in your heart that's been closed, severe mitral stenosis, or a specific stent in your heart artery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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