Clin2
NCT06490731Possibly a fitRecruiting

Comparing two sedatives for ICU recovery after bowel surgery

Haemodynamic Rebound

Treatments studied

Part of Heart & circulation clinical trials.

This trial tests whether dexmedetomidine or ketamine is better at reducing inflammation and keeping blood pressure stable in patients recovering from emergency abdominal surgery. It may help doctors choose the best sedation for you after surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
2 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have had emergency surgery on your bowels (for problems like a hole, blockage, or infection).
  • You are in the intensive care unit (ICU) and will need medicine to keep you calm and help you breathe with a ventilator.
  • You have an infection in your belly that affects your organs.
  • You are not allergic to ketamine or dexmedetomidine.
  • You are not pregnant, and do not have severe heart, liver, or kidney failure.
  • You have not received muscle relaxant drugs in your first 48 hours in the ICU.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06756178Not yet recruiting· Early Phase 1
Comparing two sedatives to prevent confusion after heart surgery

This study compares two sedative medications (remimazolam and dexmedetomidine) to see which one better prevents confusion or disorientation (called delirium) after heart surgery. Participants receive one of the two medicines during their operation, and researchers monitor them for signs of delirium during recovery.

Asyut
NCT07678216Not yet recruiting
Comparing sedatives for brain swelling after injury

This trial compares three common sedative medications used to control pressure inside the skull after a traumatic brain injury. The goal is to see which medication works best and is safest for recovery.

Asyut, Asyut Governorate
NCT07308756Recruiting· Phase 4
Study on two drugs for better recovery after surgery

This trial tests if giving two medicines, dexmedetomidine and esketamine, during and after surgery can help you feel better and recover more comfortably. It is for adults having general anesthesia for at least one hour who will use a patient-controlled pain pump afterward.

Beijing, Beijing Municipality
NCT07434310Not yet recruiting· Phase 3
Medicine to improve pain relief and recovery after bowel surgery

This study tests whether a sedative medicine called dexmedetomidine, given during bowel surgery, can help reduce pain and speed up recovery compared to usual care. It may be especially helpful for adults having laparoscopic-assisted bowel surgery.

Toronto, Ontario
NCT07874919Not yet recruiting· Phase 4
Comparing two sedation drug combos for emergency procedures

This study compares two different combinations of sedative medicines to see which one works better for adults who need a short procedure in the emergency department while awake but relaxed. It aims to find a safer and more comfortable way to keep patients calm during procedures lasting under 30 minutes.

Seeb, Muḩāfaz̧at Masqaţ
NCT06767358Not yet recruiting· Phase 3
Ketamine for sedation in the intensive care unit

This study tests whether ketamine, a sedative and painkiller, works better than usual sedatives in ICU patients who need help breathing. If you qualify, taking part may help reduce the amount of other sedatives you need.

Hamilton, Ontario

Hear when a new Haemodynamic Rebound trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.