Closed-loop stimulation for Parkinson's disease
Part of Brain & nervous system clinical trials.
This trial tests a new way to adjust deep brain stimulation (DBS) in real time, based on brain signals, to better control symptoms like speech problems, freezing, and motor fluctuations. It aims to improve daily life for people with Parkinson's who have had DBS for at least 6 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Parkinson's disease and have had deep brain stimulation (DBS) in a brain area called the STN, with the implant placed at least 6 months ago.
- You have symptoms like speech difficulty, freezing episodes, or motor fluctuations that are not well controlled by your current DBS settings.
- Your DBS device is a Percept™ PC or RC system, and it can detect brain signals (called local field potentials) on at least one side.
- You are able to safely switch to adaptive DBS, use the remote control on your own, and visit the DBS center regularly, according to your doctor.
- Your DBS electrodes are working properly and have good signal quality, and your stimulation is not primarily on the most ventral or dorsal contacts.
- You agree to allow your electronic health record data to be used for medical research.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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