Second stem cell transplant for graft failure
Part of Blood & lymphatic clinical trials.
This trial tests a second transplant using a half-matched donor for people whose first transplant failed. It may help if you have a blood cancer and are otherwise healthy enough for another procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a blood cancer like leukemia or lymphoma.
- Your first stem cell transplant (from a half-matched donor) failed to work.
- It's been less than 6 months since that first transplant.
- You are 14 years old or older.
- You do not have an active infection or active graft-versus-host disease (GVHD).
- Your liver, kidneys, and heart are working well enough.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a modified second stem cell transplant for people whose first transplant failed. It uses half-matched (haploidentical) donor cells to try to restore healthy blood cells and treat the cancer.
This trial studies a second chance treatment for people whose transplant donor cells stopped working (“graft failure”). It uses a haploidentical (half-matched) donor transplant plus cyclophosphamide after the transplant to try to get the new cells to take and recover safely.
This study tests whether giving extra stem cells from your original donor can help your blood cell counts recover after a transplant. It is for people whose new immune system has not fully engrafted or whose counts are dangerously low.
This trial tests whether a stem cell transplant from a fully matched sibling donor can help people with serious blood disorders like sickle cell disease or thalassemia. It aims to replace the faulty blood system with a healthy one from the donor.
This study tests whether umbilical cord blood cells can help patients whose blood counts have dropped again after a stem cell transplant. It may be an option for people who have recovered initially but later develop low blood cell levels.
This trial studies treatment after a first stem cell transplant fails to produce lasting blood recovery. It may help people who need a second transplant because their counts never fully recovered or then dropped again.
Hear when a new Graft Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.