Muscle relaxation levels in severe ARDS patients
Treatments studied
Part of Lungs & breathing clinical trials.
This study is testing whether different levels of muscle relaxation (called neuromuscular blockade) during breathing support can improve lung function in people with serious ARDS. It might help doctors choose the best relaxation level for patients on a breathing machine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have moderate to severe ARDS (a serious breathing condition) and your doctor thinks you need a muscle relaxant to help with breathing.
- You are between 18 and 85 years old.
- You are willing to sign a form saying you agree to join the study.
- You are not allergic to the muscle relaxant drugs used in this study.
- You do not have any open wounds on your chest or belly, or any lung tumors or transplants.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares a more careful ventilation approach for people with severe lung breathing failure (ARDS). It aims to improve outcomes by using a specific strategy for how the ventilator controls breathing.
This study tests how changing a patient's body tilt and adjusting a ventilator's settings can help open up collapsed parts of the lungs. It may help patients with severe lung failure.
This trial tests whether combining two treatments—medications that relax muscles (neuromuscular blocking agents) and lying on your stomach (prone positioning)—can reduce lung damage in people with severe ARDS on a breathing machine.
This study tests whether partially relaxing the breathing-related muscles can help people with severe low oxygen while they are on a breathing machine. It may improve how well the lungs work by changing the way the muscles affect breathing.
This trial compares two ways of giving muscle-relaxing medication to patients on breathing machines with severe lung injury. The study tests whether one approach helps patients breathe better or recover faster than the other.
This trial tests if different levels of muscle relaxation during abdominal surgery affect lung function and breathing problems after surgery. It may help patients who are having open abdominal surgery under general anesthesia lasting over an hour.
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