Sentinel node biopsy after chemo for initial node-positive breast cancer
Part of Cancer clinical trials.
This trial checks whether a less invasive sentinel lymph node biopsy (removing just a few nodes) can safely replace full lymph node removal for people whose breast cancer and underarm lymph nodes responded well to chemotherapy. It is for patients who initially had 1 to 3 involved nodes and now appear cancer-free in the armpit.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be able to carry out your daily activities with little or no help (ECOG 0-1).
- Your breast cancer stage before chemotherapy was T1, T2, or T3 (tumor up to 5 cm) with 1 to 3 lymph nodes under the arm involved (cN1).
- After chemotherapy, the tumor and lymph nodes must have shrunk enough that they appear normal on exam or imaging (ycN0).
- You cannot have had surgery or radiation therapy on the same side as this breast cancer before.
- You must not have another cancer (except certain skin cancers) in the past 5 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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