Comparing two acid reducers for healing stomach ulcers after ESD
Treatments studied
Part of Digestive system clinical trials.
This trial compares two medicines that reduce stomach acid to help heal ulcers that form after a procedure called ESD, which removes abnormal stomach tissue. The goal is to see if one medicine works better and has fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You are scheduled for or have had a procedure called ESD to remove a stomach growth or early cancer, and the ulcer left behind is 3 cm (about 1.2 inches) or smaller.
- Your blood clots normally (you don't have a bleeding disorder).
- You are not pregnant, breastfeeding, or planning to become pregnant during the study.
- You do not have severe liver, heart, or kidney disease, active cancer, or alcohol dependence.
- You are not taking blood-thinning medicines or anti-inflammatory painkillers (like aspirin or ibuprofen) long-term.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares an IV “acid-suppressing” medicine (PPI infusion) with acid pills (oral PPIs) after doctors treat a bleeding peptic ulcer endoscopically. It may help prevent re-bleeding by keeping stomach acid low while the ulcer heals.
This trial compares two medicines—vonoprazan and esomeprazole—to see which is better at healing acid damage to the esophagus (erosive esophagitis). If you have had heartburn and an endoscopy confirmed inflammation, you may be eligible for this study.
This trial tests vonaprazan (two doses) against esomeprazole to see which better heals moderate-to-severe reflux esophagitis (a damaged esophagus from acid reflux) in 8 weeks. You may qualify if you have had heartburn or regurgitation for at least a month and your doctor found grade B, C, or D damage on an endoscopy.
This study compares two treatments that reduce stomach acid after a bleeding ulcer has been repaired with an endoscope. It aims to find which one is better at preventing the ulcer from bleeding again.
This study compares two medications—vonoprazan and esomeprazole—to see which one heals acid reflux-related damage in the esophagus better after POEM surgery for achalasia. If you have had POEM and now have heartburn and moderate to severe esophagitis, this trial may help find the best treatment for you.
This trial compares two different antibiotic combinations to treat H. pylori, a common stomach bacteria that causes indigestion and ulcers. One uses a newer acid-blocking medicine (vonoprazan) and the other uses a standard one (esomeprazole), both paired with antibiotics.
Hear when a new Ulcers, Gastric trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.