Comparing two heartburn drugs after POEM surgery
Treatments studied
Part of Digestive system clinical trials.
This study compares two medications—vonoprazan and esomeprazole—to see which one heals acid reflux-related damage in the esophagus better after POEM surgery for achalasia. If you have had POEM and now have heartburn and moderate to severe esophagitis, this trial may help find the best treatment for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have had POEM surgery for achalasia
- You have heartburn or regurgitation symptoms for at least 4 weeks
- You have moderate to severe esophagitis (grade B, C, or D) confirmed by endoscopy 3 months after POEM
- You are willing to take study medication and follow the study plan
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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