IV medicine versus pills to stop bleeding stomach ulcers
Treatments studied
Part of Digestive system clinical trials.
This trial compares an IV “acid-suppressing” medicine (PPI infusion) with acid pills (oral PPIs) after doctors treat a bleeding peptic ulcer endoscopically. It may help prevent re-bleeding by keeping stomach acid low while the ulcer heals.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- An endoscopy showed a non-variceal upper GI bleed source such as a peptic ulcer (not bleeding from veins)
- The ulcer was actively treated during endoscopy (such as clipping or heat to stop bleeding)
- Doctors confirmed the bleeding was controlled after treatment and watching briefly
- You cannot be pregnant or breastfeeding
- You must be willing and able to give consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies medicines to help stop bleeding from coming back after you’ve had an “idiopathic” stomach/upper gut ulcer bleed. It may help by reducing ulcer re-bleeding risk in people who don’t have common causes like H. pylori or common ulcer-triggering drugs.
This trial compares two medicines that reduce stomach acid to help heal ulcers that form after a procedure called ESD, which removes abnormal stomach tissue. The goal is to see if one medicine works better and has fewer side effects.
This trial tests whether taking a high dose of omeprazole by mouth can help control bleeding from a peptic ulcer that looks high-risk on endoscopy. It may be aimed at lowering the chance of bleeding again after your procedure.
This study compares two treatments that reduce stomach acid after a bleeding ulcer has been repaired with an endoscope. It aims to find which one is better at preventing the ulcer from bleeding again.
This trial tests whether a common acid-reducing medicine (a proton pump inhibitor) helps people with cirrhosis who are having bleeding from enlarged veins in the esophagus. The goal is to see if it improves outcomes after emergency treatment.
This trial compares a potassium-competitive acid blocker to a proton pump inhibitor to help prevent stomach or intestinal bleeding in people at high risk who take blood-thinning medicines. It may help reduce dangerous GI bleeding while you stay on heart/stroke medicines.
Hear when a new Proton Pump Inhibitors trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.