Early acid-reducing drug for kidney injury after severe bleeding
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether giving a common acid-reducing medication (a proton pump inhibitor, or PPI) early after severe bleeding from trauma can help protect the kidneys from injury. It compares this early treatment to usual care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have gone to the emergency room with severe bleeding from a traumatic injury.
- Your blood pressure was very low (systolic ≤ 90) and heart rate fast (≥ 108), or your systolic blood pressure was extremely low (≤ 70) upon arrival.
- You are not on dialysis or kidney replacement therapy.
- You do not have a known allergy to proton pump inhibitor medications (like omeprazole, pantoprazole, etc.).
- You are not pregnant and are not a prisoner.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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