Preventing kidney injury after heart surgery with a stomach acid drug
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests whether giving a common stomach acid medication (a proton pump inhibitor) before, during, and after heart surgery can help prevent acute kidney injury. If you are at moderate to high risk for kidney problems after surgery, this study may be a good fit.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 90 years old
- You are scheduled for elective heart surgery that uses a heart-lung machine
- You have a moderate to high risk of kidney injury after surgery (based on a standard scoring system)
- Your kidney function before surgery is not severely reduced (eGFR of 30 or higher)
- You are not on dialysis or pregnant
- You do not have any allergies to proton pump inhibitors or certain other conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving a common acid-reducing medication (a proton pump inhibitor, or PPI) early after severe bleeding from trauma can help protect the kidneys from injury. It compares this early treatment to usual care.
This study tests whether giving the amino acid L-arginine soon after heart surgery can help prevent acute kidney injury (a sudden drop in kidney function). If you're recovering in the ICU after heart surgery, this may help protect your kidneys.
This study tests whether giving amino acids (protein building blocks) during heart surgery can help protect your kidneys from damage. If you are having heart surgery and are at high risk, this treatment might reduce the chance of kidney problems afterward.
This study looks at a protein in the blood that may help predict kidney damage after heart surgery. It aims to find ways to protect kidney function during and after the operation.
This trial looks at whether a specific heart-surgery technique (called CLCVP) can help protect kidney function soon after surgery. It is mainly for adults with otherwise normal kidney tests before certain types of heart operations.
This study tests whether a drug called R2R01 can help protect your kidneys during major heart surgery. Heart surgery can sometimes damage the kidneys, and this trial is looking to see if this new medication reduces that risk.
Hear when a new Acute Kidney Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.