Endoscopic surgery vs. radiation for early-stage nasal cancer
Part of Cancer, Ear, nose & throat, Mouth & dental clinical trials.
This trial compares two treatments for stage I nasopharyngeal cancer (a type of nasal cancer). It tests whether a minimally invasive surgery (endoscopic surgery) is as good as or better than radiation therapy. It may be an option for people whose cancer is small and hasn't spread to lymph nodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of nasopharyngeal cancer called non-keratinized carcinoma or carcinoma in situ (confirmed by biopsy).
- Your cancer is stage I (T1N0M0) according to the 8th edition of the UICC/AJCC staging system.
- Your lymph nodes in the neck and behind the nose are small (less than 0.6 cm) and not cancerous on a PET/CT scan.
- Your doctor says your general health and daily activity level is good (Karnofsky score above 70).
- You are willing to follow the study plan, including follow-up visits and treatments.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two treatments for newly diagnosed Stage I nasopharyngeal cancer: surgery alone versus surgery followed by a lower dose of radiation. The goal is to see if adding a gentler radiation dose can prevent the cancer from coming back without too many side effects.
This trial compares two approaches for people with early-stage nasopharyngeal cancer that can be removed with surgery. It tests whether giving less intense chemotherapy and radiation after surgery works as well as a standard dose, with fewer side effects.
This trial tests whether a minimally invasive surgery done through the nose can help people newly diagnosed with early-stage nasopharyngeal cancer. It looks for patients who have not had prior cancer treatment and who are healthy enough for the procedure and follow-up.
This trial compares two treatment plans for newly diagnosed, operable nasopharyngeal cancer: adding surgery plus targeted chemoradiation versus standard chemoradiation alone. It aims to see whether the surgery-based plan improves control of the cancer and related outcomes.
This trial studies whether lowering the radiation dose to a smaller area around the tumor is safe and effective for people with newly diagnosed nasopharyngeal cancer that has not spread. It may reduce side effects while still curing the cancer.
This trial tests a new type of radiation therapy that adjusts in real-time to treat nasopharyngeal cancer. It is for people who have not received prior radiation and have no distant spread of cancer.
Hear when a new Nasopharyngeal Carcinoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.