Surgery plus targeted chemoradiation versus standard chemoradiation
Treatments studied
Part of Cancer, Ear, nose & throat, Mouth & dental clinical trials.
This trial compares two treatment plans for newly diagnosed, operable nasopharyngeal cancer: adding surgery plus targeted chemoradiation versus standard chemoradiation alone. It aims to see whether the surgery-based plan improves control of the cancer and related outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have newly diagnosed nasopharyngeal cancer that doctors confirm by biopsy (non-keratinized type).
- Your tumor and lymph nodes in the neck/behind the throat can be removed with surgery before starting chemotherapy.
- Your cancer stage fits T1 to T3 and N0–N3 with no distant spread (M0), based on scans and exams.
- Your general health is good enough for treatment (performance status score 0–1).
- Blood tests and organ function (kidneys, liver, blood counts, clotting) meet specific minimums.
- You can take part in follow-up visits and sign the consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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