Testing a new Alzheimer's drug for moderate disease
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests a new drug (BnH-015B) for people with moderate Alzheimer's disease. It also includes a small group of healthy young men for comparison. The goal is to see if the drug is safe and how it works in the body.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are either a healthy man aged 19–45 (Part I) or a person with moderate Alzheimer's disease aged 55–85 (Part II).
- For Part II: You must have a diagnosis of moderate Alzheimer's with an MMSE score of 10–19 and a CDR global score of 2, and it must be within the last 5 years.
- You must have a positive amyloid PET scan and high levels of certain proteins (P-tau181 and osteopontin) in your blood.
- You need a steady caregiver to help you during the entire study.
- Your weight must be between 55 and 90 kg (121–198 lbs) and your BMI between 18 and 30.
- You cannot have certain heart problems, other types of dementia, or unstable psychiatric conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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