Clin2
NCT06540833Possibly a fitRecruiting

Study of ITI-1284 for psychosis in Alzheimer's disease

Psychosis Associated With Alzheimer's Disease

Treatments studied

Part of Brain & nervous system, Mental health clinical trials.

This trial tests an experimental drug, ITI-1284, to see if it can safely reduce psychosis (hallucinations or delusions) in people with Alzheimer's disease. It may be an option for patients who have both Alzheimer's and related psychotic symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
370 people
Ages
55 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with Alzheimer's disease and have psychosis symptoms like hallucinations or delusions
  • You have a family member or friend who can act as your caregiver and help with study tasks
  • You have had these symptoms for at least a few weeks and they are not caused by another illness or medication
  • Your thinking and memory abilities are moderately impaired (MMSE score between 6 and 24)
  • You are not taking other medications that affect the brain, unless approved by the study doctor

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07459660Enrolling by invitation· Phase 2
Long-term study of ML-007C-MA for Alzheimer's psychosis

This trial tests a long-term treatment (ML-007C-MA) for people with Alzheimer's disease who have psychosis. It is for those who already completed an earlier study with the same drug and may benefit from continuing it. The goal is to see if ongoing treatment is helpful and safe.

Anaheim, California
NCT06887192Recruiting· Phase 2
Testing ML-007C-MA for Alzheimer's Psychosis

This trial tests a study drug called ML-007C-MA to see if it can safely reduce hallucinations and delusions in people with Alzheimer's disease who also have psychosis. If you or your loved one has Alzheimer's and has been experiencing false beliefs or seeing/hearing things that aren't there for at least two months, this study may be an option.

Phoenix, Arizona
NCT05511363Recruiting· Phase 3
Study of a new medicine for psychosis in Alzheimer's disease

This trial tests a new drug called KarXT to see if it can safely reduce hallucinations and delusions in people with Alzheimer's disease. If you or a loved one has Alzheimer's and experiences these symptoms, this study might offer a new treatment option.

Homewood, Alabama
NCT06126224Recruiting· Phase 3
Testing KarXT for Alzheimer's-related psychosis

This clinical trial tests an investigational oral medication called KarXT for treating psychosis (hallucinations or delusions) in people with Alzheimer's disease. The study aims to see if the drug can safely reduce these symptoms.

Chandler, Arizona
NCT06651567Recruiting· Phase 2
Study of a new drug for agitation in Alzheimer's disease

This study tests an experimental medication, ITI-1284, to see if it can safely reduce agitation in people with Alzheimer's disease. Agitation can include restlessness, aggression, or irritability, and this drug aims to help manage those symptoms.

Anaheim, California
NCT06194799Enrolling by invitation· Phase 3
Long-term ACP-204 for Alzheimer's psychosis

This study tests a long-term medicine (ACP-204) for people with Alzheimer's disease who also have psychosis (hallucinations or delusions). If you took part in the earlier ACP-204 study, this open-label extension lets you continue receiving the medicine to see how well it works over time.

Costa Mesa, California

Hear when a new Psychosis Associated With Alzheimer's Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.