Clot-busting drug for late-window stroke guided by MRI
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a clot-busting drug called tenecteplase given later than usual (4.5 to 9 hours after stroke symptoms) to people whose MRI shows the stroke may still be reversible. The goal is to see if it helps reduce disability after a stroke.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old.
- Your stroke started between 4.5 and 9 hours ago (or you woke up with symptoms).
- An MRI scan shows a small stroke that is not yet fully visible on standard images, and the damaged area is not too large.
- Your stroke severity score is between 4 and 25 (moderate symptoms).
- You have not had a prior stroke or major disability before this one.
- You are not planning to have a procedure to remove the clot (endovascular treatment).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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