Surgery vs medication for pituitary tumors
Part of Brain & nervous system, Cancer, Hormones & metabolism clinical trials.
This study compares two treatments for a type of pituitary tumor called a prolactinoma. It looks at whether surgery or medication (bromocriptine) works better. The tumor must be smaller and not invade nearby structures, as determined by an MRI.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your blood test shows a very high prolactin level (at least 3 times the normal upper limit).
- An MRI shows a pituitary tumor that is grade 0 to 2 on the Knosp scale (meaning it is small and has not spread into nearby tissues).
- You are not taking antidepressants or other psychiatric medications.
- You are not allergic to bromocriptine, and you are able to have surgery if needed.
- For women: you are not infertile due to surgery (like hysterectomy or removal of both ovaries), and you have not had no menstrual periods for more than 2 years.
- You do not have severe or life-threatening conditions, like a coma or brain herniation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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