Clot-busting drug after stroke if on blood thinner
Part of Brain & nervous system, Heart & circulation clinical trials.
This study looks at whether giving a clot-busting medicine (IV thrombolysis) is safe and effective for people who have had a stroke and also recently took a direct oral anticoagulant (DOAC). If you've taken a DOAC in the last 48 hours, this trial may help doctors decide the best treatment for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a stroke due to a blood clot (ischemic stroke) within the last 12 hours.
- Your stroke symptoms are moderate or worse (NIHSS score of 2 or more).
- You took a DOAC blood thinner within the last 48 hours, or you take one regularly but the last dose time is unknown.
- No signs of bleeding in the brain on your first CT or MRI scan.
- You are not pregnant or breastfeeding.
- You can give consent to join the study (if required at your hospital).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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