Clot-busting medicine for mild stroke without limb weakness
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether giving a clot-busting drug (alteplase) within 4.5 hours helps people who have a mild stroke with symptoms like vision problems, facial drooping, or trouble speaking, but no weakness in an arm or leg.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a stroke that is mild (NIHSS score of 5 or less) with no arm or leg weakness, but you have other symptoms like vision changes, face drooping, or trouble speaking.
- You started having symptoms within the last 4.5 hours (or woke up with symptoms within 4.5 hours of the midpoint of your sleep).
- You are 18 years or older.
- You do not plan to have a procedure to remove a clot (endovascular treatment).
- You have not had a major bleed in the brain, recent head injury, or certain conditions that increase bleeding risk.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This trial tests if a clot-dissolving medicine can help people who had a mild ischemic stroke and also had a prior stroke in the last 3 months. It aims to see if the treatment is safe and effective for this specific group.
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This trial tests whether giving a clot-dissolving medicine (alteplase or tenecteplase) is safe and effective for people who have had a stroke and are taking a blood thinner (DOAC) like apixaban or rivaroxaban. It aims to see if this treatment can still be given within a few hours of the stroke.
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