Studying spinal fluid in babies with spina bifida
Part of Brain & nervous system, Genetic & congenital, Mental health clinical trials.
This study looks at the fluid around the brain and spinal cord (called cerebrospinal fluid or CSF) in newborns and fetuses with spina bifida, compared to babies without the condition. The goal is to understand how this fluid may affect brain development, which could lead to better treatments in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- For newborns with spina bifida: your baby must be under 1 year old and scheduled for closure surgery at GOSH.
- For control group 1: your baby must have hydrocephalus (not due to spina bifida) and be scheduled for shunt surgery.
- For control group 2: your infant must be under 1 year old and scheduled for spinal surgery for conditions like a tethered spinal cord.
- For fetuses: you must be 22 to 24 weeks pregnant with a spina bifida diagnosis, and the surgery will be at UCLH.
- You and your baby must not have other major medical conditions that could affect the spinal fluid.
- If your baby has had previous spinal surgery, they cannot take part.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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