Study of new drugs for stage III lung cancer with rare gene changes
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests whether giving treatment before surgery (neoadjuvant therapy) can help people with stage III lung cancer that has certain rare gene changes. The goal is to see if this approach can shrink the tumor enough to allow surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have stage III non-small cell lung cancer that cannot be removed with surgery right now.
- Your lung cancer has a rare gene change (like EGFR exon20ins, ROS1 fusion, RET fusion, NTRK fusion, MET exon14 skipping, HER2, BRAF V600E, KRAS G12C, or ALK fusion).
- You have not had any previous treatment for your lung cancer.
- You are between 18 and 75 years old.
- You are willing to provide blood and tumor tissue samples before and after treatment.
- Your overall health is good enough for daily activities (ECOG score 0 or 1).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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