Clin2
NCT06566482Possibly a fitRecruiting

Medicine for pain after surgery in sleep apnea patients

Obstructive Sleep ApneaSurgeryDexmedetomidineEsketaminePostoperative Sleep Quality

Treatments studied

Part of Brain & nervous system, Lungs & breathing clinical trials.

This trial tests a combination of two medicines (dexmedetomidine and esketamine) given in small doses to help with pain after surgery. It is for people who have sleep apnea or are at risk for it, and who are having chest or belly surgery with a scope.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
100 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are between 18 and 80 years old.
  • You have sleep apnea or are at moderate-to-high risk for it (based on a simple screening questionnaire).
  • You are scheduled for chest or belly surgery using a scope (thoracoscopic or laparoscopic) that will last at least 1 hour.
  • You will receive a pain pump (patient-controlled IV pain medicine) after surgery.
  • You do not have certain serious health conditions like severe heart, liver, kidney, or brain problems, or a history of certain mental health disorders.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06859892Recruiting· Phase 4
Drug combo study for better sleep after major surgery

This study tests whether a combination of two medicines, dexmedetomidine and esketamine, can help improve sleep problems after major non-heart surgery. You may be eligible if you are having planned surgery lasting at least one hour and will use a pain pump after surgery.

Beijing
NCT07308756Recruiting· Phase 4
Study on two drugs for better recovery after surgery

This trial tests if giving two medicines, dexmedetomidine and esketamine, during and after surgery can help you feel better and recover more comfortably. It is for adults having general anesthesia for at least one hour who will use a patient-controlled pain pump afterward.

Beijing, Beijing Municipality
NCT07525999Not yet recruiting· Phase 4
Pain Relief After Spine Surgery Using Two Medications

This study tests whether combining two medications—dexmedetomidine and esketamine—given during and after spine surgery can reduce chronic pain that sometimes develops months or years after surgery. If it works, it could help prevent long-term pain problems for people having back or neck surgery.

Beijing, Beijing Municipality
NCT07523321Not yet recruiting· Phase 4
Pain relief after spine surgery with two medications

This study tests a combination of two medications (dexmedetomidine and esketamine) to help manage moderate-to-severe pain after spine surgery. You would receive these drugs through an IV pump that you control to give yourself pain relief as needed.

Beijing, Beijing Municipality
NCT07753785Not yet recruiting
Comparing two pain relievers after surgery for sleep apnea patients

This trial compares two pain medicines given after surgery to see which provides better pain relief with fewer side effects in people who have obstructive sleep apnea. It aims to improve safety and comfort for sleep apnea patients recovering from non-cardiac surgery.

Beijing
NCT06087510Recruiting· Phase 4
Different doses of esketamine and dexmedetomidine for pain after scoliosis surgery

This trial tests two different doses of esketamine and dexmedetomidine to see which provides better pain relief after scoliosis correction surgery. It aims to improve your recovery and long-term outcomes.

Beijing, Beijing Municipality

Hear when a new Obstructive Sleep Apnea trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.