Experimental cell therapy for severe graft-versus-host disease
Treatments studied
Part of Immune system & allergy clinical trials.
This trial tests a new immune cell treatment for people with severe graft-versus-host disease (GVHD) that hasn't improved with standard medications like ruxolitinib. The goal is to see if these special cells can calm the immune attack and help manage symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 1 and 70 years old.
- You have grade II to IV GVHD (a moderate to severe form) after a stem cell transplant, and it did not get better with steroids or other treatments like ruxolitinib.
- You are able to take care of yourself (ECOG score 0 to 3), meaning you are up and around at least half the day.
- Your life expectancy is estimated to be more than 12 weeks.
- If you could become pregnant, you must have a negative pregnancy test before starting and use effective birth control during the study and for 6 months after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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