Cell therapy for hard-to-treat chronic graft-versus-host disease
Part of Blood & lymphatic, Immune system & allergy clinical trials.
This study tests a new cell therapy called GT729 for people with chronic graft-versus-host disease (cGVHD) that hasn't improved with at least two previous treatments. The therapy is given as an injection and aims to help control the immune system reaction that causes cGVHD.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have had a stem cell transplant from a donor (allogeneic transplant).
- You currently have active chronic graft-versus-host disease (cGVHD) that needs treatment.
- You have already tried at least two different treatments for cGVHD, and they didn't work or stopped working.
- Your blood counts and organ function (kidney, liver) are within certain minimum levels.
- You are not pregnant (if applicable) and agree to use effective contraception.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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