XL092 for advanced prostate cancer after PSMA therapy
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This trial tests a new oral drug, XL092, for men with metastatic castration-resistant prostate cancer that has progressed after PSMA-targeted radiation therapy (Lu-177 PSMA-617). It aims to see if the drug can slow down the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have prostate cancer that has spread to other parts of the body (metastatic).
- You have received PSMA-targeted radiation treatment (Lu-177 PSMA-617) and your cancer continued to grow.
- Your cancer is castration-resistant (hormone therapy is no longer controlling it).
- You are able to take care of yourself (ECOG performance status 0, 1, or 2).
- Your liver, kidney, and blood cell counts are acceptable based on blood tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial studies whether a PSMA-targeted treatment using 177Lu can help men with prostate cancer that has spread and is growing despite hormone treatment. It may help if your scan shows high PSMA in the tumor and your blood counts and organ function are adequate.
This study tests a radioactive drug called Lu-PSMA-617 for men with advanced prostate cancer that has spread and is no longer responding to hormone therapy. The drug targets a protein on cancer cells to deliver radiation directly to the tumor.
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