Clin2
NCT06569485Possibly a fitRecruiting

Trilaciclib plus chemo for new DLBCL patients

DLBCL

Part of Blood & lymphatic, Cancer clinical trials.

This study tests whether adding a drug called trilaciclib to standard chemotherapy can help people with newly diagnosed Diffuse Large B-Cell Lymphoma. It aims to see if this combination keeps blood counts healthier and improves treatment outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
38 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older.
  • You must have a new diagnosis of Diffuse Large B-Cell Lymphoma (a type of blood cancer) that hasn't been treated yet.
  • You must be in generally good health to receive the study treatment.
  • You cannot have other active cancers or serious health problems like uncontrolled heart disease.
  • Women who can have children must have a negative pregnancy test and agree to use birth control during and after the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06750991Not yet recruiting· Phase 2
A new treatment for high-risk large B-cell lymphoma with genetic changes

This study tests a new treatment combination (CD-RCHOP, likely a form of chemotherapy with an antibody) for people with a high-risk type of diffuse large B-cell lymphoma that has certain genetic changes (TP53 mutation and 17p deletion). It aims to see if this approach is safe and effective for this specific group.

Shanghai, Shanghai Municipality
NCT06701357Recruiting· Phase 2
New drug combo for untreated aggressive lymphoma

This trial tests a new treatment combination for people newly diagnosed with a fast-growing type of lymphoma called diffuse large B-cell lymphoma (DLBCL) that has changes in two proteins, MYC and BCL2, making it a 'double expressor' lymphoma. The goal is to see if adding another drug to standard chemo-immunotherapy can improve results.

Shanghai, Shanghai Municipality
NCT07398638Not yet recruiting· Phase 1/Phase 2
Study of lisatoclax with standard chemoimmunotherapy for untreated large B-cell lymphoma

This trial tests a new drug called lisatoclax added to the usual chemotherapy and antibody treatment for people newly diagnosed with diffuse large B-cell lymphoma (DLBCL). The goal is to see if adding this drug helps the standard treatment work better.

Guangzhou, Guangdong
NCT07035379Not yet recruiting· Phase 1/Phase 2
New drug plus standard chemo for untreated DLBCL

This study tests a new drug (TRS005) combined with standard chemotherapy (cyclophosphamide, doxorubicin, and prednisone) as a first treatment for people with CD20-positive DLBCL. The goal is to see if this combination is safe and effective in controlling the lymphoma.

Beijing, Beijing Municipality
NCT07712588Not yet recruiting· Phase 2/Phase 3
Adding birelentinib to standard chemo for newly diagnosed aggressive lymphoma

This trial tests whether adding a new targeted drug called birelentinib to the standard chemotherapy combination (R-CHOP) helps people with newly diagnosed aggressive lymphoma. It aims to improve the chances of remission and reduce the risk of the lymphoma coming back.

Chongqing, Chongqing Municipality
NCT06854445Recruiting· Phase 2
TQB2825 plus chemo for relapsed/refractory DLBCL

This trial tests a new drug called TQB2825 combined with chemotherapy for people with diffuse large B-cell lymphoma (DLBCL) that has come back or not responded to at least one prior treatment. It aims to see if this combination can help when other treatments haven't worked and stem cell transplant is not an option.

Wuhu, Anhui

Hear when a new DLBCL trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.